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  1. jubei33 is offline
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    Posted On:
    9/22/2011 8:54am


     Style: Boxing, Solar Ray Attack

    --
    Hell yeah! Hell no!
    Bread mould is possible, if you don't care too much about quantity and just to get something. You'd probably run into the same problems early researchers did with trying to get strains that would produce large amounts of the skeleton. But its very possible. I've kind of always wanted to try and DIY it, actually.
    http://woodwardswhiskey.wordpress.com/

    He was punching him like the collective karmic debt he'd accrued was coming to collections, mostly on his face.
  2. Cake of Doom is online now

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    Posted On:
    9/22/2011 8:59am


     Style: Holiday Judo

    --
    Hell yeah! Hell no!
    Now is your chance. Run and be free.

    Would low quality of said drugs make any sort of long term storage an issue (for drugs affected by temperature, moisture etc...)?
  3. jubei33 is offline
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    Posted On:
    9/22/2011 9:38am


     Style: Boxing, Solar Ray Attack

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    Hell yeah! Hell no!
    quality, most definitely, but also depends on what the contaminations are. The first point of issue is that you obviously wouldn't want to get an infection from a bacterially contaminated, poorly produced product, so quality would be your first priority for self-administration. Anything living in that environment would probably be something that would give you a few problems to deal with; I think the power of prayer would help in this case.

    Second point, it depends on the drug and its formulation. Liquid suspensions often have shelf lives of just a few weeks. Capsules usually last much longer, but like you mentioned heat and moisture will break these down too. If serum concentrations don't reach an effective dose level, then you run the risk of producing resistant strains, which are a bitch to treat now (look at our problems with MRSA,etc).

    Sterilize your equipment, etc...
    http://woodwardswhiskey.wordpress.com/

    He was punching him like the collective karmic debt he'd accrued was coming to collections, mostly on his face.
  4. Cake of Doom is online now

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    Posted On:
    9/22/2011 9:46am


     Style: Holiday Judo

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    Hell yeah! Hell no!
    Have you ever heard of or watched a program called Rough Science? This reminds me very much of that, except this is interesting whilst the program dealt with running out of moisturiser and other such faggotry.

    Could a diluted solution of the acid be used for sterilization? <ignorance> can liquid suspensions survive freezing or would this damage the make up of it?
  5. jubei33 is offline
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    Posted On:
    9/22/2011 10:07am


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    --
    Hell yeah! Hell no!
    what acid? Are we talking about a kind of (many) penicillin? or the sulfa drugs. They do use some sulfa drug solutions for antiseptics, esp. in the case of severe burns, but a soln of alcohol (etc) would be a better bet than using something that has the ability to select out strong mutant strains.

    Freezing could probably preserve it longer, but you'd still have the issue of water vapor in the freezer as it sublimes as frost. Blister packs aren't enough to prevent this kind of degradation. If we're talking liquid suspensions then you'd have issues of re-solvation.

    A lot of these synthesis using the 6-amino penicilianic acid backbone are done at low temperatures 0 C and below. I know amoxicillin is made this way.
    http://woodwardswhiskey.wordpress.com/

    He was punching him like the collective karmic debt he'd accrued was coming to collections, mostly on his face.
  6. Cake of Doom is online now

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    Posted On:
    9/22/2011 10:31am


     Style: Holiday Judo

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    Hell yeah! Hell no!
    Well that answers those questions. Now; bread mould and crackers!
  7. The Question is offline
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    Posted On:
    7/21/2012 10:39pm

    Join us... or die
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    Hell yeah! Hell no!
    Bd, that is an enormous wall of text there. Couldn't you have summarized that **** a little bit to make it less monolithic. The **** is wrong with you?

    Fucking cool though. Maybe next time I'll straight up make that **** instead of buying it and will therefore have more money to spend on totally appalling pornography.

    Incidentally, why the **** would you think about and write all this **** though?

    Edit: Goddamn, did I just necro a thread? This **** popped up after I clicked the "new posts" search tab.

    The **** is going on? Is the universe expanding in a different direction again?
    Last edited by The Question; 7/21/2012 10:43pm at .
    Quote Originally Posted by Goju - joe
    being a dick with skill is only marginally better than being a dick without skill.
  8. jubei33 is offline
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    Posted On:
    7/22/2012 9:50pm


     Style: Boxing, Solar Ray Attack

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    Hell yeah! Hell no!
    Quote Originally Posted by The Question View Post
    Fucking cool though. Maybe next time I'll straight up make that **** instead of buying it and will therefore have more money to spend on totally appalling pornography.
    Why are you having some issues with UTIs that some former girlfriends should be told about?

    Plain and simple, I like chemistry, especially medicine and the development and production of them. And I like spreading a little bit of interest in it when I can.

    I'm glad you liked it.

    DID you know that cytoplasmic enzymes typically fold in a manner that positions hydrophillic regions out towards the cytoplasm, while the more hydrophobic regions are pushed to the inside of the protein. The most interesting thing is that this is a spontaneous process, an effect of emergent complexity of the simple arrangemnet of amino acids in a sequence. As the entropy of the chain becomes more ordered, the more water is displaced from ionic binding with the amino acids and randomness or entropy increases overall for the system.

    Furthermore, experiments have shown that a protein's folding is specific and once it has been denatured fully, including severing disulfide bridges, it can be reinstated if the chemicals used to cause the denaturation were removed. This say something important about a protein's natural shape or conformation.
    http://woodwardswhiskey.wordpress.com/

    He was punching him like the collective karmic debt he'd accrued was coming to collections, mostly on his face.
  9. The Question is offline
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    Posted On:
    7/23/2012 11:55pm

    Join us... or die
     Style: Striking/Grappling/Poking

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    Hell yeah! Hell no!
    Quote Originally Posted by jubei33 View Post
    Why are you having some issues with UTIs that some former girlfriends should be told about?
    **** no. Well, I hope not anyway, and if I did I would need something stronger than sulfamethoxazole or other sulfas, because E.Coli and other nasty motherfuckers that like people's urinary tracts and **** around here have begun to laugh in the face of sulfa drugs. LOL, Sulfa. Of course, if you happened to get PCP during the zombie outbreak because you were starving or whatever, then you could down some of that ****.
    Plain and simple, I like chemistry, especially medicine and the development and production of them. And I like spreading a little bit of interest in it when I can.
    I like spreading madness. One time we had a party and had no ice. Bio lab. Pop open ice storage. Not giving a **** about what kind of multidrug resistant evil was in there. Get that ****. Drinks for all. How no one got sick is a fucking miracle.
    And then there was that time we fucked around with that 200proof industrial grade ethanol, because again, we were idiots. I think I posted a thread about that on here too.
    I'm glad you liked it.
    Indeed. More zombies next time though.
    DID you know that cytoplasmic enzymes typically fold in a manner that positions hydrophillic regions out towards the cytoplasm, while the more hydrophobic regions are pushed to the inside of the protein. The most interesting thing is that this is a spontaneous process, an effect of emergent complexity of the simple arrangemnet of amino acids in a sequence.
    Of course I fucking new that. This isn't 1996, son. They taught us that **** in the same breath as "this is how detergent works" and then I almost told the teacher to **** off for no apparent reason.
    As the entropy of the chain becomes more ordered, the more water is displaced from ionic binding with the amino acids and randomness or entropy increases overall for the system.
    I never actually thought about this, but it stands to reason.
    Furthermore, experiments have shown that a protein's folding is specific and once it has been denatured fully, including severing disulfide bridges, it can be reinstated if the chemicals used to cause the denaturation were removed. This say something important about a protein's natural shape or conformation.
    Really? So aforementioned girl who did or did not give me a UTI did something fucked up to her hair, right (why these girls put chemicals and **** to straighten or perm or whatever the **** they call it is a motherfucking mystery to me. I can't stand that ****. That thick natural hair is fucking beautiful, AND, it doesn't break when you grab it while energetically pounding the fluff out of that ass for all of 75 seconds. Anyway, what you're saying is that is she washed her hair really hard, that **** would go back to normal? Because that sounds fucking ridiculous. Or is it that the denaturing chemicals have seeped deep into the kertain layers and **** and can't be removed by washing? This would make sense. So what would be needed then is some wily fucking formula that can get in there and get that nasty denaturing/perming **** out of there? Fucking hell. BD, get on that ****. We must reverse the perms! No longer will hair come off in my hand while I'm using it to pull myself into violent thrusts while yelling **** like "I'm about to a-POP-tosis inside you, bitch!!!".

    Fucking cool, yo.
    Quote Originally Posted by Goju - joe
    being a dick with skill is only marginally better than being a dick without skill.
  10. jubei33 is offline
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    Posted On:
    7/26/2012 4:58am


     Style: Boxing, Solar Ray Attack

    --
    Hell yeah! Hell no!
    Quote Originally Posted by The Question View Post
    Really? So aforementioned girl who did or did not give me a UTI did something fucked up to her hair, right (why these girls put chemicals and **** to straighten or perm or whatever the **** they call it is a motherfucking mystery to me. I can't stand that ****. That thick natural hair is fucking beautiful, AND, it doesn't break when you grab it while energetically pounding the fluff out of that ass for all of 75 seconds. Anyway, what you're saying is that is she washed her hair really hard, that **** would go back to normal? Because that sounds fucking ridiculous. Or is it that the denaturing chemicals have seeped deep into the kertain layers and **** and can't be removed by washing? This would make sense. So what would be needed then is some wily fucking formula that can get in there and get that nasty denaturing/perming **** out of there? Fucking hell. BD, get on that ****. We must reverse the perms! No longer will hair come off in my hand while I'm using it to pull myself into violent thrusts while yelling **** like "I'm about to a-POP-tosis inside you, bitch!!!"
    I usually just cum in their hair, but you can stick with your way.

    Speaking of lipids, You know cholesterol? you know how its "bad for you"? Pssssst--Its more complicated than that. It's necessary for membrane repair and growth. Children without it (through genetic deficit) grow slowly and deformed. Its a large component of cell membranes, which creates sections of uniformity called lipid rafts. These guys are necessary to act as hydrophobic regions where membrane proteins like receptors can be sandwiched in. The reason this works is the usual hydrophillic out/hydrophobic inside set up of cytoplasmic proteins is reversed. So you get a matching of these respective zones, like water mixes with water, oil with oil.
    http://woodwardswhiskey.wordpress.com/

    He was punching him like the collective karmic debt he'd accrued was coming to collections, mostly on his face.
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